Arteriosclerosis is a condition in which cholesterol-rich deposits, known as atheromas, accumulate on the inner walls of the arteries. Over time, these deposits narrow the arteries and reduce the flow of blood to tissues and organs.
The progression of arteriosclerosis is influenced by several factors, the most significant being:
high blood cholesterol
high blood pressure
diabetes
cigarette smoking
These factors contribute to the gradual deterioration of the arteries and increase the risk of serious cardiovascular events.
When arteriosclerosis affects the heart, it can lead to:
angima
angina
heart attack
an increased risk of sudden cardiac death
When it affects the brain, it may cause cerebral thrombosis, which can result in:
muscular paralysis
loss of cognitive capacity
an increased risk of dementia
Arteriosclerosis may also affect the aorta and the arteries of the legs, causing pain, difficulty in walking and, in severe cases, necrosis or gangrene.